15. 048 - Blood

Step 01
tHE idea

The Objective

The scientific journal editor proposes illustration services to authors who wish to publish in their peer-reviwed journal.
As scientific graphic designer, I then intervene to adapt the author's graphical abstract or figure to journal guidelines and style.

Step 02
tHE brief

Editor

Blood - American Society of Hematology
Peer-reviewed journal - IF: 20.3

Article

Journal style

Editor's guidelines focus on the format of the figure: 492 px x 263.2 px (formatted in picas).
The Avenir font is preferred and should not be smaller than 8 pt

Colors

Colors should be adapted for color-blind people: elements that need to be identified or differentiated need to be seen by at least the most common types of color blindness (Protanopia and Deuteranopia).

Step 03
tHE abstract

Restoring NK cell functions in AML relapse

In this issue of Blood, Wang et al demonstrate that glycoprotein A repetitions predominant (GARP)–mediated activation of TGF-β1 by regulatory T cells (Tregs) downregulates the effector functions of natural killer (NK) cells in the bone marrow of patients with acute myeloid leukemia (AML) with early relapse after allogeneic hematopoietic cell transplantation (allo-HCT), and that pharmacologic blockade of TGF-β1 signaling using galunisertib or anti-TGF-β1 antibodies can restore the killer instinct of human NK cells.

Step 04
tHE sketch

Step 05
Final image

Thank you